Mira Asriningtyas works as an independent curator and writer. She completed De Appel Curatorial Program in 2017 (Amsterdam) and RAW Academie 6: CURA in 2019 (Dakar). In her curatorial practice, she is especially interested in working on site‐specific multidisciplinary projects within the practice of everyday life as a means to address socio‐political issues and history. She has curated exhibition and public programs off-sites and in art institutions such as De Appel Art Center (Amsterdam); Stedelijk Museum (Amsterdam); Fondazione Sandretto Re Rebaudengo (Turin); KKF (Yogyakarta); ISCP (New York); MAIIAM Contemporary Art Museum (Chiang Mai); Our Museum (Taipei) among others. Her essays have been published internationally in books, exhibition catalog, monograph, journals, and online publications including Ocula, PARSE Journal and Stedelijk Studies among others. 

In 2011, she co‐founded LIR Space, an art space that turned nomadic into LIR (curator collective). For the past 8 years, their program ranges from laboratories for experimental exhibition approach, research‐based art projects, public programs, residency, and alternative art education platforms. Over the years, the institutional format was perpetually renewed and in 2019, LIR Space turned nomadic as LIR. LIR's projects are characterized by multi‐disciplinary collaboration in order to foster continuous transgenerational transmission of knowledge, memory, and history. LIR’s latest project is #CuratedByLIR solo exhibition series (2018 - 2023) and the 3rd Pollination (2020‐2021) initiated by The Factory Contemporary Arts Centre (Ho Chi Minh City). Titled "Of Hunters & Gatherers", the 3rd Pollination project is composed of an exhibition, symposia and dedicated website in multiple sites, co‐hosted by MAIIAM Contemporary Art Museum (Chiang Mai), Selasar Sunaryo Art Space (Bandung), The Factory Contemporary Arts Centre (Ho Chi Minh City), with the support of SAM Funds for Arts and Ecology (Indonesia) and The Gray Centre for Art & Inquiry (Chicago). 

In 2017, she started a biennial site‐specific project titled "900mdpl" in Kaliurang, an aging   resort village under Mt.Merapi volcano. The program invites local and international artists for a research residency and creates a socially‐engaged archive of the space presented as a multi-site exhibition and a transient museum. The 1st edition (2017) presented portraits of the community and their living space. The 2nd edition (2019) was an attempt to pinpoint the small village within the map of Indonesian bigger history. The 3rd edition (2022) was presented in two cycles, looking upon the relationship between mythology and how it affects the environmental sustainability of the area.

In 2024, Mira Asriningtyas together with Dito Yuwono are appointed as the new directors of CEMETI - Institute for Arts and Society in Yogyakarta, Indonesia.